Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
R. Kristensen, J. B. Andersen, M. Levin Rybtke, C. U. Jansen, B. G. Fritz, R. Kiilerich, J. Uhd, T. Bjarnsholt, K. Qvortrup, T. Tolker-Nielsen, M. Givskov, T. H. Jakobsen
The paper identifies two compounds that inhibit quorum sensing in Pseudomonas aeruginosa by inducing the MexEF-oprN efflux pump, reducing QS-regulated virulence factors.
bioRxiv · Oct 27, 2023 · PreprintMicrobiology