Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath
L. Butruille, P. Jubin, E. Martin, M.-S. Aigrot, M. Lhomme, J.-B. Fini, B. Demeneix, B. Stankoff, C. Lubetzki, B. Zalc, S. Remaud
This study shows that PFOS exposure disrupts oligodendrogenesis and myelin function, impairing remyelination and potentially contributing to myelin disorders like multiple sclerosis.
bioRxiv · May 30, 2023Pharmacology & Toxicology