Author

M. M. Pruitt

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Manning· 1 shared H. Gali· 1 shared L. G. Zamalloa· 1 shared N. M. Hermance· 1 shared R. L. Flynn· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. L. Manning

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1 paper

Recent·Most cited

RB loss sensitizes cells to replication-associated DNA damage by PARP inhibition

L. G. Zamalloa, M. M. Pruitt, N. M. Hermance, H. Gali, R. L. Flynn, A. L. Manning

This study shows that RB loss increases DNA damage in cancer cells by promoting PARylation, and PARP inhibition sensitizes these cells to replication stress and reduced viability.

bioRxiv · Mar 25, 2023 · PreprintCell Biology