Author

N. M. Hermance

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. L. Manning· 3 shared B. Navarro-Serer· 1 shared C. P. Herlihy· 1 shared D. Mercadante· 1 shared E. A. Crowley· 1 shared E. P. Childers· 1 shared H. Gali· 1 shared L. G. Zamalloa· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

A. L. Manning

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Author profile →

3 papers

Recent·Most cited

RB loss sensitizes cells to replication-associated DNA damage by PARP inhibition

L. G. Zamalloa, M. M. Pruitt, N. M. Hermance, H. Gali, R. L. Flynn, A. L. Manning

This study shows that RB loss increases DNA damage in cancer cells by promoting PARylation, and PARP inhibition sensitizes these cells to replication stress and reduced viability.

bioRxiv · Mar 25, 2023 · PreprintCell Biology

Suppression of chromosome instability limits acquired drug resistance

E. A. Crowley, N. M. Hermance, C. P. Herlihy, A. L. Manning

This study shows that suppressing chromosome instability reduces acquired drug resistance in non-small cell lung cancer by altering molecular mechanisms, without affecting tumor growth.

bioRxiv · Jul 10, 2020Cancer Biology

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes

B. Navarro-Serer, E. P. Childers, N. M. Hermance, D. Mercadante, A. L. Manning

This study shows Aurora A inhibition disrupts spindle pole clustering in cells with supernumerary centrosomes, leading to mitotic catastrophe and aneuploid daughter cells.

bioRxiv · Feb 2, 2019Cancer Biology