MAVS regulates the quality of the antibody response to West-Nile Virus
M. O'Ketch, C. Larson, S. Williams, J. L. Uhrlaub, R. Wong, N. R. Deshpande, D. Schenten
This study shows that MAVS, an RLR signaling adaptor, is critical for the quality of the antibody response to WNV, as MAVS-deficient mice produced low-affinity IgM antibodies despite normal antigen levels.
bioRxiv · Dec 15, 2019Immunology