Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors
K. Nishino, Y. Arai, K. Takasawa, M. Toyoda, M. Yamazaki-Inoue, T. Sugawara, H. Akutsu, K. Nishimura, M. Ohtaka, M. Nakanishi, A. Umezawa
The paper compares epigenetic differences in human iPSCs generated by three different vectors and finds Sendai virus generates the fewest aberrant methylation sites.
bioRxiv · Jun 25, 2018Cell Biology