The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients
S. Pyfrom, B. Paneru, J. J. Knox, M. P. Cancro, S. Posso, J. H. Buckner, M. Anguera
The paper investigates X-chromosome inactivation (XCI) dynamics in human B cells, finding dysregulated XCI and aberrant X-linked gene expression in SLE patients.
bioRxiv · Nov 25, 2020Immunology