Author

J. J. Knox

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Au· 1 shared A. Cucalon· 1 shared A. G. Schmidt· 1 shared A. Griffiths· 1 shared A. Honko· 1 shared A. R. Burns· 1 shared A. Ryan· 1 shared A. S. Vaidya· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Au

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3 papers

Recent·Most cited

Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release

S. Harrington, J. J. Knox, A. R. Burns, K.-L. Choo, A. Au, M. Kitner, C. Haeberli, J. Pyche, C. D'Amata, Y.-H. Kim, J. Volpatti, M. Guiliani, J. Snider, V. Wong, B. M. Palmeira, , P. Roy

A C. elegans-based screening pipeline identifies a selective nematicide that also potentiates acetylcholinesterase inhibitors.

bioRxiv · Mar 12, 2022 · PreprintPharmacology & Toxicology

Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates

N. Zabaleta, W. Dai, U. Bhatt, J. A. Chichester, J. Sanmiguel, R. Estelien, K. T. Michalson, C. Diop, D. Maciorowski, W. Qi, E. Hudspeth, A. Cucalon, C. D. Dyer, M. B. Pampena, J. J. Knox, , L. H. Vandenberghe

This paper evaluates an AAV-based COVID-19 vaccine in mice and non-human primates, showing sustained neutralizing antibodies and memory T-cells, with room-temperature stability and scalable production.

bioRxiv · Jan 5, 2021 · PreprintImmunology

The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients

S. Pyfrom, B. Paneru, J. J. Knox, M. P. Cancro, S. Posso, J. H. Buckner, M. Anguera

The paper investigates X-chromosome inactivation (XCI) dynamics in human B cells, finding dysregulated XCI and aberrant X-linked gene expression in SLE patients.

bioRxiv · Nov 25, 2020Immunology