Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
A. J. Stock, P. Gonzalez-Paredes, L. Previato de Almeida, S. D. Kosanke, S. Chetlur, H. Budde, P. Wakenight, T. A. Zwingman, A. B. Rosen, E. Allenspach, K. J. Millen, J. H. Buckner, D. J. Rawlings, J. A. Gorman
This study shows the IFIH1-A946T risk variant increases T1D risk in females but not males by enhancing IFN I signaling and altering immune cell profiles in NOD mice.
bioRxiv · Jan 20, 2024Immunology
H. R. Waterman, M. J. Dufort, S. E. Posso, M. Ni, L. Z. Li, C. Zhu, P. Raj, K. D. Smith, J. H. Buckner, J. A. Hamerman
The paper shows IgA1 autoantibodies enhance pDC IFN responses when combined with IgG in RNA-containing immune complexes through FcR receptor interaction.
bioRxiv · Sep 7, 2023Immunology
C. E. Gustafson, Z. Thomson, Z. He, E. Swanson, K. Henderson, M.-P. L. Pebworth, L. Y. Okada, A. T. Heubeck, C. R. Roll, V. Hernandez, M. D. Weiss, P. C. Genge, J. Reading, J. R. Giles, S. Manne, , P. J. Skene
The study identifies age-related differences in naive T cell compartments between children and adults, showing distinct molecular reprogramming in CD4 and CD8 subsets.
bioRxiv · Oct 4, 2022 · PreprintImmunology
W. Anderson, F. Barahmand-pour-Whitman, P. S. Linsley, K. Cerosaletti, J. H. Buckner, D. J. Rawlings
This study edits the PTPN22 R620W variant in T cells to show it enhances low avidity TCR responses, contributing to autoimmunity risk.
bioRxiv · Jul 21, 2022Immunology
M. Chriswell, A. R. Lefferts, M. Clay, A. Hsu, J. Seifert, M. L. Feser, M. Maerz, C. Rims, M. Bloom, E. A. Bemis, M. K. Demoruelle, K. D. Deane, E. A. James, J. H. Buckner, W. H. Robinson, , K. A. Kuhn
Subdoligranulum spp. targeted by RA-relevant autoantibodies activate T cells in RA patients and induce autoantibodies and joint swelling in mice.
bioRxiv · Jun 9, 2022 · PreprintImmunology
M. Smithmyer, A. E. Wiedeman, D. A. G. Skibinski, A. K. Savage, C. Acosta-Vega, S. Scheiding, V. H. Gersuk, S. A. Long, J. H. Buckner, C. Speake
The paper detects sample annotation errors in cytometry data by comparing HLA allele expression with longitudinal and qPCR data, identifying mismatches in 2.4% of samples.
bioRxiv · Oct 26, 2021Immunology
L. So, K. Obata-Ninomiya, A. Hu, V. Muir, A. Takamori, J. Song, J. H. Buckner, R. Savan, S. Ziegler
This study shows regulatory T cells suppress CD4 T cell activation by inhibiting translation of mRNAs encoding protein synthesis machinery, highlighting translational control in immune tolerance.
bioRxiv · Sep 23, 2021Immunology
K. Lambert, K. G. Moo, A. Arnett, G. Goel, K. J. Flynn, C. Speake, A. E. Wiedeman, C. J. Greenbaum, S. A. Long, R. Partridge, J. H. Buckner, B. Khor
The paper uses permutational analysis to reveal advanced immune aging in Down syndrome and type 1 diabetes.
bioRxiv · Sep 13, 2021 · PreprintImmunology
S. Pyfrom, B. Paneru, J. J. Knox, M. P. Cancro, S. Posso, J. H. Buckner, M. Anguera
The paper investigates X-chromosome inactivation (XCI) dynamics in human B cells, finding dysregulated XCI and aberrant X-linked gene expression in SLE patients.
bioRxiv · Nov 25, 2020Immunology
A. K. Savage, M. V. Gutschow, T. Chiang, K. Henderson, R. Green, M. Chaudhari, E. Swanson, A. T. Heubeck, N. Kondza, K. C. Burley, P. C. Genge, C. Lord, T. Smith, Z. Thomson, A. Beaubien, , T. F. Bumol
This study shows that delayed blood processing causes significant changes in single-cell transcriptomes and plasma proteomes within 6 hours, potentially confounding disease-related biological variance.
bioRxiv · Oct 18, 2020Immunology
H. Bolouri, C. Speake, D. Skibinski, S. A. Long, A. M. Hocking, D. J. Campbell, J. A. Hamerman, U. Malhotra, J. H. Buckner, BRI COVID-19 Research Team
This study identifies three immune clusters in COVID-19 patients correlated with disease severity and shows that immune responses change dynamically with clinical outcomes.
bioRxiv · Sep 18, 2020Immunology