Calpain-2 mediates SARS-CoV-2 entry and represents a therapeutic target
Q. Zeng, A. Antia, M. P. Chavez, S. B. Kutluay, S. Ding
This study identifies calpain-2 as a host factor facilitating SARS-CoV-2 entry and shows calpain inhibitors inhibit viral infection through an Mpro-independent pathway.
bioRxiv · Nov 29, 2022 · PreprintMicrobiology