Author

M. P. Connolly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. B. Siegel· 3 shared C. G. Brooke· 1 shared C. Shaw· 1 shared D. E. Culley· 1 shared D. J. Caruso· 1 shared E. Hawley· 1 shared H. N. Frizzo· 1 shared J. A. Garcia· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersPharmacology & Toxicology

J. B. Siegel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Computationally Designed Carbonic Anhydrase Inhibitors Derived from Sulfonamides for Treatment of Glaucoma

D. J. Caruso, M. P. Connolly, T. Q. Nguyen, J. B. Siegel

This paper designs two novel carbonic anhydrase II inhibitors derived from sulfonamides for glaucoma treatment, showing improved docking scores compared to existing drugs.

bioRxiv · Feb 25, 2023 · PreprintPharmacology & Toxicology

Phototrophic co-cultures from extreme environments: community structure and potential value for fundamental and applied research

C. Shaw, C. G. Brooke, M. P. Connolly, J. A. Garcia, M. Harmon-Smith, N. Shapiro, E. Hawley, M. Barton, S. G. Tringe, T. Glavina del Rio, D. E. Culley, R. Castenholtz, M. Hess

The paper evaluates photosynthetic co-cultures from extreme environments using 16S rRNA gene sequencing to explore their potential in understanding microbial roles in carbon and nitrogen cycling.

bioRxiv · Jun 25, 2020Microbiology

Evaluating molecular modeling tools for thermal stability using an independently generated dataset

P. Huang, S. K. S. Chu, H. N. Frizzo, M. P. Connolly, R. W. Caster, J. B. Siegel

The paper evaluates five computational tools for predicting thermal stability and soluble protein production in enzyme mutants using an expanded dataset of 51 β-glucosidase mutants.

bioRxiv · Nov 28, 2019 · PreprintBiophysics

Computationally Guided Design of Dipeptidyl Peptidase-4 Inhibitors

L. C. Reynolds, M. P. Connolly, J. B. Siegel

This study designs two new DPP-4 inhibitors using computational methods, showing improved docking scores compared to anagliptin.

bioRxiv · Sep 18, 2019 · PreprintPharmacology & Toxicology