Author

M. P. Kuehnel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

D. Jonigk· 4 shared C. Werlein· 2 shared K. E. Hostettler· 2 shared L. Knudsen· 2 shared P. Khan· 2 shared S. Blumer· 2 shared S. Savic· 2 shared A. Bjorholm Dahl· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersCell Biology

D. Jonigk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis

S. Blumer, P. Khan, N. Artysh, L. Plappert, S. Savic, L. Knudsen, D. Jonigk, M. P. Kuehnel, A. Prasse, K. E. Hostettler

The paper uses cultured human alveolar basal cells to create in vitro and in vivo models that mimic honeycomb cyst formation in idiopathic pulmonary fibrosis.

bioRxiv · Sep 19, 2023Cell Biology

In vitro culture of aberrant basal-like cells from fibrotic lung tissue

P. Khan, J. Roux, S. Blumer, L. Fang, S. Savic, L. Knudsen, D. Jonigk, M. P. Kuehnel, A. Gazdhar, T. Geiser, M. Tamm, K. E. Hostettler

The paper cultures and characterizes aberrant basal-like cells from fibrotic lung tissue, finding they co-express epithelial and mesenchymal markers and show disease-specific transcriptomic differences between IPF and other ILD patients.

Cells · Jun 2, 2022Peer-reviewedCell Biology

Ex Vivo Validation of Six FDA-Approved Non-Receptor Tyrosine Kinase Inhibitors (NRTKIs) as Antivirals to Pandemic and Seasonal Influenza A Viruses

R. Meineke, S. Stelz, M. Busch, C. Werlein, M. P. Kuehnel, D. Jonigk, G. F. Rimmelzwaan, H. Elbahesh

The paper tests six FDA-approved non-receptor tyrosine kinase inhibitors for antiviral activity against influenza A viruses in cell cultures and human lung slices, finding potent inhibition of virus replication.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology

3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography

M. Reichardt, P. Moller Jensen, V. Andersen Dahl, A. Bjorholm Dahl, M. Ackermann, H. Shah, F. Länger, C. Werlein, M. P. Kuehnel, D. Jonigk, T. Salditt

This study uses phase-contrast x-ray tomography to analyze 3D cardiac tissue structure from Covid-19 patients, revealing distinct vascular changes compared to other viral myocarditides.

eLife · Dec 21, 2021Peer-reviewedPathology