Concerted localization resets precede YAP-dependent transcription
R. P. Ghosh, J. M. Franklin, Q. Shi, M. P. Reddick, J. T. Liphardt
The paper shows that YAP-dependent transcription is activated by cycles of rapid nuclear-cytoplasmic shuttling, not just nuclear enrichment, and identifies factors that induce these cycles.
bioRxiv · Feb 4, 2019 · PreprintBiophysics