Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity
M. Duennwald, L. T.-W. Lin, A. R. Razzaq, S. E. Di Gregorio, S. Hong, B. Charles, M. H. Lopes, F. Beraldo, V. Prado, M. Prado
This study shows Hsp90 and Sti1 modulate TDP-43 misfolding, inclusion formation, and toxicity in neuronal cells.
bioRxiv · Oct 8, 2020Cell Biology