Author

M. R. Breese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. G. Lee· 1 shared A. Heslin· 1 shared A. L. Koehne· 1 shared A. Spillinger· 1 shared A. Sweet-Cordero· 1 shared A. T. Shah· 1 shared A. Tulpule· 1 shared A.-F. Galic· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. G. Lee

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy

S. Menon, D. Gracilla, M. R. Breese, Y. P. Lin, F. S. Dela Cruz, T. Feinberg, E. De Stanchina, A.-F. Galic, H. Allegakoen, s. perati, N. Wen, A. Heslin, M. Horlbeck, J. S. Weissman, A. Sweet-Cordero, , A. Tulpule

This study shows FET fusion oncoproteins disrupt DNA repair by inhibiting ATM signaling, making ATR inhibitors a potential therapy for FET rearranged cancers.

bioRxiv · Apr 30, 2023 · PreprintCancer Biology

Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities

C. R. Schott, A. L. Koehne, L. C. Sayles, E. P. Young, C. Luck, K. Yu, A. G. Lee, M. R. Breese, S. G. Leung, A. T. Shah, H. Xu, H.-Y. Liu, A. Spillinger, I. H. Behroozfard, K. D. Marini, , E. A. Sweet-Cordero

The paper develops and characterizes new osteosarcoma PDX models with varying metastatic capacities to study disease biology and test therapeutic interventions.

bioRxiv · Jan 19, 2023Cancer Biology