Author

M. R. Friedlander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

B. Fromm· 2 shared I. Biryukova· 2 shared M. Tarbier· 2 shared A. A. Noegel· 1 shared A. Dziedziech· 1 shared A. Hejnol· 1 shared A. Jex· 1 shared B. Balan· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

B. Fromm

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Author profile →

5 papers

Recent·Most cited

Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity

B. Edelbroek, J. Kjellin, I. Biryukova, Z. Liao, T. Lundberg, A. A. Noegel, L. Eichinger, M. R. Friedlander, F. Soderbom

The paper identifies miRNAs in Amoebozoa, showing they are present in unicellular and multicellular species, but not required for multicellularity evolution.

bioRxiv · Oct 19, 2023Evolutionary Biology

Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut

M. Mohammed, A. Dziedziech, V. Sekar, M. Ernest, T. L. Alves E Silva, B. Balan, S. N. Emami, I. Biryukova, M. R. Friedlander, A. Jex, M. Jacobs-Lorena, J. Henriksson, J. Vega-Rodriguez, J. Ankarklev

This study uses single-cell transcriptomics to analyze Plasmodium falciparum development in the mosquito midgut, identifying transcriptional trajectories and stress responses, including genes encoding intrinsically disordered proteins.

bioRxiv · Apr 5, 2022Microbiology

Ancient microRNA profiles of a 14,300-year-old canid are taxonomically informative and give glimpses into gene regulation from the Pleistocene

B. Fromm, M. Tarbier, O. Smith, L. Dalen, T. M. Gilbert, M. R. Friedlander

The paper analyzes ancient microRNA profiles from a 14,300-year-old canid, showing they are taxonomically informative and provide insights into Pleistocene gene regulation.

bioRxiv · Dec 16, 2019Evolutionary Biology

Combined mRNA and protein single cell analysis in a dynamic cellular system using SPARC

J. Reimegard, M. Danielsson, M. Tarbier, J. Schuster, S. Baskaran, S. Panagiotou, N. Dahl, M. R. Friedlander, C. J. Gallant

This study introduces SPARC, a method to co-profile mRNA and protein in single cells, showing they provide complementary information about cellular states.

bioRxiv · Sep 13, 2019 · PreprintCell Biology

Evolutionary implications of the microRNA- and piRNA complement of Lepidodermella squamata (Gastrotricha)

B. Fromm, J. P. Tosar, F. Aguilera, M. R. Friedlander, L. Bachmann, A. Hejnol

This study identifies miRNA and piRNA complements in Lepidodermella squamata, supporting a close evolutionary relationship between gastrotrichs and flatworms.

bioRxiv · Jan 4, 2019Evolutionary Biology