Author

M. R. K. Mofrad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:Hi-C· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Z. Jahed· 2 shared G. Yerima· 1 shared H. Shams· 1 shared J. Ornowski· 1 shared N. Domkam· 1 shared W. Miao· 1 shared Z. Haydari· 1 shared Z. Yang· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

Z. Jahed

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3 papers

Recent·Most cited

Cell BiologybioRxivFeb 2, 2023

Force transmission and SUN-KASH higher-order assembly in the LINC complex models

G. Yerima, N. Domkam, J. Ornowski…·M. R. K. Mofrad

This study compares force transmission in two LINC complex models using molecular dynamics simulations, finding that the 6:6 higher-order model offers greater flexibility under compressive and shear forces.

DOI 10.1016/j.bpj.2023.11.001

mechanistic / dynamical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 18, 2020

The intriguing dynamics of chromatin folding and assembly

Z. Yang, W. Miao, M. R. K. Mofrad

This study introduces a dynamic model of chromatin folding using molecular dynamics simulations and shows it can reproduce Hi-C contact matrices and reveal dynamics' impact on chromatin structure.

DOI 10.1101/2020.02.18.953398

humanHi-C

𝕏 PostBluesky

BiophysicsbioRxivJun 6, 2019

Kindlin Assists Talin to Promote Integrin Activation

Z. Haydari, H. Shams, Z. Jahed, M. R. K. Mofrad

This study reveals how kindlin enhances talin-mediated integrin IIb{beta}3 activation through molecular dynamics simulations.

DOI 10.1016/j.bpj.2020.02.023

biophysical modelingprotein folding & dynamics

𝕏 PostBluesky