Author

Z. Jahed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

B. Cui· 5 shared C.-T. Tsai· 5 shared X. Li· 4 shared W. Zhang· 3 shared A. R. Roy· 2 shared M. R. K. Mofrad· 2 shared Y. Yang· 2 shared A. F. McGuire· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersBiophysics

B. Cui

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Engineering cell and nuclear morphology on nano topography by contact-free protein micropatterning

E. Sarikhani, D. Pushpa Meganathan, K. Rahmani, C.-T. Tsai, A. Marquez-Serrano, X. Li, F. Santoro, B. Cui, L. Hyldgaard Klausen, Z. Jahed

This study uses laser-assisted micropatterning to engineer cell and nuclear morphology on nanopillar platforms, showing disrupted nuclear-cell shape coupling and enhanced endocytosis on nanopillars.

bioRxiv · Jun 5, 2023 · PreprintBiophysics

Curved adhesions mediate cell attachment to soft matrix fibres in 3D

W. Zhang, C.-H. Lu, M. L. Nakamoto, C.-T. Tsai, A. R. Roy, C. E. Lee, Y. Yang, Z. Jahed, X. Li, B. Cui

This study identifies curved adhesions as a new type of integrin-mediated adhesion that forms in soft matrices and is crucial for 3D cell migration.

bioRxiv · Mar 16, 2023 · PreprintCell Biology

Force transmission and SUN-KASH higher-order assembly in the LINC complex models

G. Yerima, N. Domkam, J. Ornowski, Z. Jahed, M. R. K. Mofrad

This study compares force transmission in two LINC complex models using molecular dynamics simulations, finding that the 6:6 higher-order model offers greater flexibility under compressive and shear forces.

bioRxiv · Feb 2, 2023Cell Biology

Nanocrown electrodes for reliable and robust intracellular recording of cardiomyocytes and cardiotoxicity screening

Z. Jahed, Y. Yang, C.-T. Tsai, E. P. Foster, A. F. McGuire, H. Yang, A. Liu, C. Forro, Z. Yan, X. Jiang, M.-T. Zhao, W. Zheng, X. Li, T. Li, A. Pawlosky, , B. Cui

This paper develops nanocrown electrodes for reliable intracellular recording of cardiomyocytes and demonstrates their use in cardiotoxicity screening.

bioRxiv · Sep 28, 2021 · PreprintBioengineering

Exploring cell surface-nanopillar interactions with 3D super-resolution microscopy

A. R. Roy, W. Zhang, Z. Jahed, C.-T. Tsai, B. Cui, W. E. Moerner

This paper introduces a 3D single-molecule super-resolution microscopy method to study protein distribution at the nano-bio interface with 10-20 nm precision.

bioRxiv · Jun 21, 2021Biophysics

Nanoscale surface topography reduces focal adhesions and cell stiffness by enhancing integrin endocytosis

X. Li, L. H. Klausen, W. Zhang, Z. Jahed, C.-T. Tsai, T. L. Li, B. Cui

This paper shows that nanoscale surface topography reduces focal adhesions and cell stiffness by enhancing integrin endocytosis, mimicking the effects of soft substrates on rigid materials.

bioRxiv · Jun 18, 2021Bioengineering

Kindlin Assists Talin to Promote Integrin Activation

Z. Haydari, H. Shams, Z. Jahed, M. R. K. Mofrad

This study reveals how kindlin enhances talin-mediated integrin IIb{beta}3 activation through molecular dynamics simulations.

bioRxiv · Jun 6, 2019Biophysics