Author

M. R. Mehaffey

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Biochemistry· 1

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. E. Escobar· 1 shared J. Brodbelt· 1 shared J. E. Mayfield· 1 shared K. Kathuria· 1 shared M. R. Robinson· 1 shared N. A. Prescott· 1 shared N. T. Burkholder· 1 shared S. Irani· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

E. E. Escobar

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1 paper

Recent·Most cited

BiochemistrybioRxivMay 28, 2019

Tyr1 phosphorylation promotes the phosphorylation of Ser2 on the C-terminal domain of RNA polymerase II by P-TEFb

Y. Zhang, J. E. Mayfield, S. Irani…·J. Brodbelt

The paper shows Tyr1 phosphorylation directs P-TEFb to phosphorylate Ser2 on RNA polymerase II CTD, altering its specificity and expanding CTD modification coding potential.

DOI 10.7554/elife.48725

ChIP-seqexperimental assay

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