PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma
R. Boudra, B. L. Patenall, S. King, D. Wang, S. A. Best, J. Y. Ko, S. Xu, M. G. Padilla, C. D. Schmults, S. R. Barthel, C. G. Lian, M. R. Ramsey
This study identifies BNC1-PRMT1 as a transcriptional axis promoting SCC growth, showing PRMT1 inhibition reduces tumor size without affecting migration.
bioRxiv · Mar 27, 2023 · PreprintCancer Biology