Author

C. G. Lian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Approach:microscopy & imaging analysis· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. J. Nirmal· 3 shared G. F. Murphy· 3 shared P. K. Sorger· 3 shared Z. Maliga· 3 shared A. A. Chen· 2 shared S. Santagata· 2 shared Y.-A. Chen· 2 shared A. K. Dewan· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

A. J. Nirmal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence

Z. Maliga, D. Y. Kim, A.-T. N. Bui, J.-R. Lin, A. K. Dewan, G. F. Murphy, A. J. Nirmal, C. G. Lian, P. K. Sorger, N. R. LeBoeuf

This study compares CyCIF and IHC for immune profiling in ICI-induced dAEs, finding CyCIF provides more detailed single-cell characterization of immune infiltrates.

bioRxiv · Apr 3, 2023 · PreprintImmunology

PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

R. Boudra, B. L. Patenall, S. King, D. Wang, S. A. Best, J. Y. Ko, S. Xu, M. G. Padilla, C. D. Schmults, S. R. Barthel, C. G. Lian, M. R. Ramsey

This study identifies BNC1-PRMT1 as a transcriptional axis promoting SCC growth, showing PRMT1 inhibition reduces tumor size without affecting migration.

bioRxiv · Mar 27, 2023 · PreprintCancer Biology

The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution

A. J. Nirmal, Z. Maliga, T. Vallius, B. Quattrochi, A. A. Chen, C. A. Jacobson, R. J. Pelletier, C. Yapp, R. Arias-Camison, Y.-A. Chen, C. G. Lian, G. F. Murphy, S. Santagata, P. K. Sorger

The paper uses spatial techniques to study immune evasion and immunoediting in primary melanoma, finding localized immunosuppressive environments and coexistence of invasion and regression.

bioRxiv · May 23, 2021Cancer Biology

Micro-region transcriptomics of fixed human tissue using Pick-Seq

Z. Maliga, A. J. Nirmal, N. G. Ericson, S. A. Boswell, L. U'Ren, R. Podyminogin, J. Chow, Y.-A. Chen, A. A. Chen, D. M. Weinstock, C. G. Lian, G. F. Murphy, E. P. Kaldjian, S. Santagata, P. K. Sorger

Pick-Seq enables deep spatial transcriptomic profiling of fixed human tissue, revealing transcriptional differences in tumor invasion, proliferation, and immuno-editing.

bioRxiv · Mar 18, 2021 · PreprintCancer Biology