E2F4 as a single multifactorial target against Alzheimer's disease
N. Lopez-Sanchez, M. Ramon-Landreau, C. Trujillo, A. Garrido-Garcia, J. M. Frade
This study shows that inhibiting E2F4 in Alzheimer's mice reduces inflammation, Aβ proteostasis issues, and cognitive decline, suggesting E2F4 as a therapeutic target.
bioRxiv · May 8, 2020 · PreprintPathology