ErpY-like lipoprotein of Leptospira outsmart host complement regulation by acquiring complement regulators, activating alternate pathway, and intervening membrane attack complex
S. Hota, M. S. Hussain, M. Kumar
This study shows that the ErpY-like lipoprotein of Leptospira binds complement regulators, activates the alternate pathway, and reduces membrane attack complex deposition, aiding immune evasion.
bioRxiv · May 27, 2021 · PreprintMicrobiology