Proteomic analysis of the Aggregation Factor from the sponge Clathria (Microciona) prolifera suggests an ancient protein domain toolkit for allorecognition in animals
F. Ruperti, M. Dzieciatkowska, M. S. Pankey, C. S. Asensio, D. Anselmetti, X. Fernandez-Busquets, S. A. Nichols
The paper uses proteomics to identify AF components in sponges and finds conserved domains suggesting an ancient toolkit for cell adhesion and allorecognition.
bioRxiv · Apr 19, 2024 · PreprintBiochemistry