Actomyosin-driven force patterning controls endocytosis at the immune synapse
A. Kumari, P. J. Saez, M. Maurin, D. Lankar, M. San Roman, R. Voituriez, K. Hennig, V. F. Boura, M. Karlsson, M. Balland, A.-M. Lennon-Dumenil, P. Pierobon
This study shows that mechanical forces at the immune synapse are spatially and temporally patterned by actomyosin dynamics, with global contractile forces at the periphery and local forces at the center, which regulate endocytosis.
bioRxiv · Oct 25, 2018Cell Biology