Author

A.-M. Lennon-Dumenil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 5 Research Focus:development & morphogenesis· 3 Assay:imaging· 3 Organism:mouse· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Maurin· 3 shared M. Piel· 3 shared D. Sanseau· 2 shared H. D. Moreau· 2 shared P. J. Saez· 2 shared R. Voituriez· 2 shared Z. Alraies· 2 shared A. Figueiredo· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

M. Maurin

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis

Z. Alraies, C. A. Rivera, M.-G. Delgado, D. Sanseau, M. Maurin, R. Amadio, G. Maria Piperno, G. Dunsmore, A. Yatim, L. Lacerda Mariano, P. Saez, M. Gratia, O. Lamiable, A. Moreau, A. Williart, , A.-M. Lennon-Dumenil

The paper identifies a shape sensing mechanism in dendritic cells that links cell motility to CCR7 expression, enabling migration to lymph nodes through ARP2/3-cPLA2 signaling.

bioRxiv · Aug 9, 2022Cell Biology

Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors

V. LAPLAUD, N. Levernier, J. Pineau, M. San-Roman, L. Barbier, P. J. Saez, A.-M. Lennon-Dumenil, P. Vargas, K. Kruse, O. DU ROURE, M. Piel, J. Heuvingh

The paper measures cortical thickness in live cells using magnetic beads and finds it is dynamic and fluctuates due to actomyosin contractility.

bioRxiv · Sep 28, 2020Biophysics

Endothelial cell invasiveness is controlled by myosin IIA-dependent inhibition of Arp2/3 activity

A. Figueiredo, P. Barbacena, A. Russo, S. Vaccaro, D. Ramalho, A. Pena, A. P. Lima, R. R. Ferreira, F. El-Marjou, Y. Carvalho, F. F. Vasconcelos, A.-M. Lennon-Dumenil, D. M. Vignevic, C. A. Franco

The paper identifies myosin IIA's role in inhibiting Arp2/3 activity to regulate endothelial tip cell protrusions during sprouting angiogenesis.

bioRxiv · Sep 8, 2020 · PreprintCell Biology

Developmentally regulated PERK activity renders dendritic cells insensitive to subtilase cytotoxin-induced integrated stress response

P. Pierre, A. Mendes, J. P. Gigan, C. Rodriguez Rodrigues, S. A. Choteau, D. Sanseau, D. Barros, C. Almeida, V. Camosseto, L. Chasson, A. W. Paton, J. C. Paton, R. J. Argüello, A.-M. Lennon-Dumenil, E. Gatti

The paper shows dendritic cells have high eIF2 phosphorylation due to PERK activation, but this does not lead to chronic ISR or translation arrest, allowing them to adapt to stress.

bioRxiv · Apr 27, 2020 · PreprintImmunology

Actomyosin-driven force patterning controls endocytosis at the immune synapse

A. Kumari, P. J. Saez, M. Maurin, D. Lankar, M. San Roman, R. Voituriez, K. Hennig, V. F. Boura, M. Karlsson, M. Balland, A.-M. Lennon-Dumenil, P. Pierobon

This study shows that mechanical forces at the immune synapse are spatially and temporally patterned by actomyosin dynamics, with global contractile forces at the periphery and local forces at the center, which regulate endocytosis.

bioRxiv · Oct 25, 2018Cell Biology

Actin filaments regulate microtubule growth at the centrosome.

M. Thery, D. Inoue, D. Obino, F. Farina, J. Gaillard, C. Guerin, L. Blanchoin, A.-M. Lennon-Dumenil

This study shows that actin filaments at the centrosome reduce microtubule growth through steric hindrance, and that cell adhesion and actin network density influence microtubule numbers.

bioRxiv · Apr 16, 2018Cell Biology

Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells

H. D. Moreau, C. Blanch-Mercader, R. Attia, Z. Alraies, M. Maurin, P. Bousso, J.-F. Joanny, R. Voituriez, M. Piel, A.-M. Lennon-Dumenil

This study shows that macropinocytosis enables immature dendritic cells to overcome hydraulic resistance, enhancing their space exploration and tissue-patrolling function, while mature dendritic cells are hindered by this resistance.

bioRxiv · Feb 27, 2018Cell Biology