Variable Mutations at the p53-R273 Oncogeic Hotspot Position Leads to Altered Properties
A. Garg, J. P. Hazra, M. Sannigrahi, S. Rakshit, S. Sinha
This study examines how different R273 mutations in p53 affect structural stability, aggregation, and toxicity, revealing distinct molecular mechanisms that may contribute to varied cancer outcomes.
bioRxiv · Jun 26, 2019Biophysics