Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis
H. Dong, J. Dumenil, F.-H. Lu, L. Na, H. Vanhaeren, C. Naumann, M. Klecker, R. Prior, C. Smith, N. McKenzie, G. Saalbach, L. Chen, T. Xia, N. Gonzalez, M. Seguela, , M. W. Bevan
The paper identifies DA1 as a ubiquitin-activated peptidase in Arabidopsis that cleaves and destabilizes E3 ligases and growth regulatory proteins to limit cell proliferation during organ development.
bioRxiv · Nov 30, 2016Plant Biology