N. Gonzalez

Identification and validation of drugs for repurposing in Glioblastoma: a computational and experimental workflow

This paper develops a computational and experimental workflow to identify and validate repurposed drugs for Glioblastoma treatment, finding that Etoposide and Cisplatin are more effective than Temozolomide.

The Zinc Finger protein SlZFP2 is essential for tomato fruit locular tissue morphogenesis

The study identifies SlZFP2 as essential for tomato locular tissue morphogenesis by altering cell cycle and endoreduplication in a gel-less mutant.

Ploidy-specific transcriptomes shed light on the heterogeneous identity and metabolism of developing pericarp cells

The paper analyzes ploidy-specific transcriptomes in tomato pericarp cells to reveal how endoreduplication influences cell identity and metabolism during fruit development.

The FW2.2/CNR protein regulates cell-to-cell communication in tomato by modulating callose deposition at plasmodesmata

This study identifies FW2.2/CNR as a transmembrane protein regulating callose deposition at plasmodesmata, thereby modulating cell-to-cell communication in tomato during fruit development.

Various tomato cultivars display contrasted morphological and molecular responses to a heat wave.

This study examines how different tomato cultivars respond morphologically and molecularly to heat waves, identifying common and specific molecular mechanisms.

Solanum lycopersicum CLASS-II KNOX genes regulate fruit anatomy via gibberellin-dependent and independent pathways.

This study shows that TKN-II genes in tomato regulate fruit anatomy through both gibberellin-dependent and independent pathways.

Association between quinolone use in food animals and gonococcal resistance to ciprofloxacin: an ecological study

This study investigates the link between quinolone use in food animals and gonococcal resistance to ciprofloxacin, finding a positive association at the country level.

SlKIX8 and SlKIX9 are negative regulators of leaf and fruit growth in tomato

This study identifies SlKIX8 and SlKIX9 as negative regulators of leaf and fruit growth in tomato, with loss-of-function mutants showing enlarged organs due to increased cell expansion.

Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis

The paper identifies DA1 as a ubiquitin-activated peptidase in Arabidopsis that cleaves and destabilizes E3 ligases and growth regulatory proteins to limit cell proliferation during organ development.