ImmunologybioRxivPreprint
A ganglioside-based senescence-associated immune checkpoint
C. Iltis, L. Seguin, L. Cervera…·J. Cherfils-Vicini
This paper identifies GD3 as a senescence-associated immune checkpoint that suppresses NK cell-mediated clearance of senescent cells, showing that targeting GD3 can enhance anti-fibrotic effects in a mouse model.
DOI 10.1101/2021.04.23.440408