Author

C. Iltis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

B. G. Neel· 1 shared C. C. Feral· 1 shared C. Davis· 1 shared C. Delannoy· 1 shared C. Zhang· 1 shared D. Sun· 1 shared D. W. Clapp· 1 shared E. Cosson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

B. G. Neel

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2 papers

Recent·Most cited

Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors

S. Farouk Sait, K.-h. Tang, S. Angus, R. Brown, D. Sun, X. Xie, C. Iltis, M. Lien, N. Socci, T. Bale, C. Davis, S. A. H. Dixon, C. Zhang, D. W. Clapp, B. G. Neel, L. F. Parada

This study shows that combining SHP2 and autophagy inhibition effectively suppresses NF1-associated MPNSTs in mouse models, suggesting a potential new treatment approach.

bioRxiv · Aug 18, 2022 · PreprintCancer Biology

A ganglioside-based senescence-associated immune checkpoint

C. Iltis, L. Seguin, L. Cervera, L. Duret, T. Hamidouch, S. Kunz, O. Croce, C. Delannoy, Y. Guerardel, F. Allain, L. Moudombi, P. Hofman, E. Cosson, J. Guglielmi, T. Pourcher, , J. Cherfils-Vicini

This paper identifies GD3 as a senescence-associated immune checkpoint that suppresses NK cell-mediated clearance of senescent cells, showing that targeting GD3 can enhance anti-fibrotic effects in a mouse model.

bioRxiv · Apr 23, 2021 · PreprintImmunology