The molecular principles governing HCMV infection outcome
M. Schwartz, M. Shnayder, A. Nachshon, T. Arazi, Y. Kitsberg, R. Levi Samia, M. Lavi, R. Kuint, R. Tsabari, N. Stern-Ginossar
This study identifies molecular factors determining HCMV infection outcomes in macrophages and monocytes using single-cell transcriptomics, revealing that viral gene expression and intrinsic ISG levels dictate productive vs. non-productive infection.
bioRxiv · Oct 31, 2022 · PreprintMicrobiology