Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
Y. Finkel, A. Nachshon, E. Aharon, T. Arazi, E. Simonovsky, M. Dobesova, A. Gluck, T. Fisher, R. J. Stanton, M. Schwartz, N. Stern-Ginossar
This study develops VECOS, a viral-encoded CRISPR screen to analyze host dependencies during cytomegalovirus infection, identifying novel factors and revealing the importance of virion assembly.
bioRxiv · Oct 30, 2023 · PreprintMicrobiology
M. Schwartz, M. Shnayder, A. Nachshon, T. Arazi, Y. Kitsberg, R. Levi Samia, M. Lavi, R. Kuint, R. Tsabari, N. Stern-Ginossar
This study identifies molecular factors determining HCMV infection outcomes in macrophages and monocytes using single-cell transcriptomics, revealing that viral gene expression and intrinsic ISG levels dictate productive vs. non-productive infection.
bioRxiv · Oct 31, 2022 · PreprintMicrobiology
T. Fisher, A. Gluck, K. Narayanan, M. Kuroda, A. Nachshon, J. C Hsu, P. J Halfmann, Y. Yahalom-Ronen, Y. Finkel, M. Schwartz, S. Weiss, C.-T. K Tseng, T. Israely, N. Paran, Y. Kawaoka, , N. Stern-Ginossar
This study investigates the role of SARS-CoV-2 nsp1 in host shutoff and immune evasion, finding it inhibits translation and induces mRNA degradation, and is critical for counteracting the IFN response.
bioRxiv · Mar 14, 2022Microbiology
B. Rozman, A. Nachshon, R. L. Samia, M. Lavi, M. Schwartz, N. Stern-Ginossar
This study examines HCMV gene expression dynamics during productive and latent infections, revealing that viral gene regulation is not a simple sequential cascade and that IE genes are uniquely repressed in latency.
bioRxiv · Jul 26, 2021Microbiology
Y. Finkel, A. Gluck, R. Winkler, A. Nachshon, O. Mizrahi, Y. Lubelsky, B. Zuckerman, B. Slobodin, Y. Yahalom-Ronen, H. Tamir, I. Ulitsky, T. Israely, N. Paran, M. Schwartz, N. Stern-Ginossar
This study identifies how SARS-CoV-2 suppresses host protein synthesis through global translation reduction, mRNA degradation, and impaired translation of immune-related transcripts.
bioRxiv · Nov 25, 2020Microbiology
S. Weingarten-Gabbay, S. Klaeger, S. Sarkizova, L. R. Pearlman, D.-Y. Chen, M. R. Bauer, H. B. Taylor, H. L. Conway, C. H. Tomkins-Tinch, Y. Finkel, A. Nachshon, M. Gentili, K. D. Rivera, D. B. Keskin, C. M. Rice, , P. C. Sabeti
The paper identifies HLA-I peptides from SARS-CoV-2 in infected cells, revealing epitopes from both canonical and out-of-frame ORFs, which could inform vaccine development.
bioRxiv · Oct 2, 2020 · PreprintImmunology
Y. Finkel, O. Mizrahi, A. Nachshon, S. Weingarten-Gabbay, D. Morgenstern, Y. Yahalom-Ronen, H. Tamir, H. Achdout, D. Stein, O. Israeli, A. Beth-Din, S. Melamed, S. Weiss, T. Isrealy, N. Paran, , N. Stern-Ginossar
This study maps the full coding capacity of SARS-CoV-2 using ribosome profiling, identifying 23 novel translated ORFs and revealing viral translation dominance over host translation.
Nature · Sep 9, 2020Peer-reviewedMicrobiology
Y. Finkel, D. Schmiedel, J. Tai-Schmiedel, A. Nachshon, M. Schwartz, O. Mandelboim, N. Stern-Ginossar
This study identifies hundreds of new ORFs and lncRNAs in HHV-6A and B genomes, revealing conserved features across betaherpesviruses.
bioRxiv · Aug 8, 2019Microbiology
M. Shnayder, A. Nachshon, B. Krishna, E. Poole, A. Boshkov, A. Binyamin, I. Maza, J. Sinclair, M. Schwartz, N. Stern-Ginossar
This study uses single-cell RNA sequencing to analyze HCMV latency and finds no evidence of a restricted latency-associated gene expression program, instead showing gene expression patterns similar to late lytic stages at lower levels.
bioRxiv · Nov 3, 2017Microbiology