Differential sorting behavior for soluble and transmembrane cargoes at the trans-Golgi network in endocrine cells.
B. H. Hummer, D. Maslar, M. Soltero Gutierrez, N. F. de Leeuw, C. S. Asensio
The paper quantifies TGN budding kinetics of constitutive and regulated secretory cargoes and reveals that transmembrane cargoes exit the TGN into non-regulated vesicles before incorporation into secretory granules.
bioRxiv · Oct 8, 2019Cell Biology