T. Günther

Population genomic history of the endangered Anatolian and Cyprian mouflons in relation to worldwide wild, feral and domestic sheep lineages

This study analyzes the population history and genetic diversity of Anatolian and Cyprian mouflons compared to other sheep lineages, finding genetic affinity with domestic sheep and disparities in diversity and mutation load.

Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region

This study analyzes ancient sheep genomes from the Baltic Sea region to show long-term continuity of short-tailed breeds and loss of genetic diversity in modern times.

Yersinia remodels epigenetic histone modifications in human macrophages

This study shows Yersinia enterocolitica modulates histone modifications in human macrophages to alter gene expression related to immune response and metabolism.

The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression

This paper shows CTCF regulates HPV18 transcript splicing and late gene expression during differentiation by controlling chromatin looping and splice site usage.

Oncogenic herpesvirus engages the endothelial transcription factors SOX18 and PROX1 to increase viral genome copies and virus production

This study shows that SOX18 and PROX1, endothelial transcription factors, regulate KSHV lytic replication and virus production in lymphatic endothelial cells.

Human cytomegalovirus nuclear capsid motility is non-directed and independent of nuclear actin bundles

This study investigates whether HCMV-induced nuclear actin bundles mediate capsid transport, finding no evidence of directed motility or active transport along nuclear F-actin.

A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

This study compares the epigenetic features of KSHV and MHV-68, showing that KSHV rapidly recruits polycomb repressive complexes through specific cis-acting sequence features, unlike MHV-68.