Author

M. Sternke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Assay:protein sequence· 3 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:protein design· 1

Frequent Co-Authors

D. Barrick· 3 shared K. W. Tripp· 2 shared C. Nixon· 1 shared M. J. Harms· 1 shared S. A. Lim· 1 shared S. Marqusee· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

D. Barrick

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3 papers

Recent·Most cited

The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins

C. Nixon, S. A. Lim, M. Sternke, D. Barrick, M. J. Harms, S. Marqusee

The paper compares consensus and ancestral protein reconstruction methods using Ribonuclease H sequences, finding that phylogenetically restricted consensus proteins are more stable than those from diverse clades.

bioRxiv · Jun 29, 2023Biophysics

Surface residues and non-additive interactions stabilize a consensus homeodomain protein

M. Sternke, K. W. Tripp, D. Barrick

The paper investigates how substitutions in a consensus homeodomain protein contribute to its stabilization, finding that surface residues and charge-conserving substitutions play key roles.

bioRxiv · Apr 19, 2021Biophysics

Consensus sequence design as a general strategy to create hyperstable, biologically active proteins

M. Sternke, K. W. Tripp, D. Barrick

This study evaluates consensus sequence design for creating stable, biologically active proteins across six families, finding high success rates in stability and function.

bioRxiv · Apr 29, 2019Biophysics