Biochemical Patterns of Antibody Polyreactivity Revealed Through a Bioinformatics-Based Analysis of CDR Loops
C. T. Boughter, M. T. Borowska, J. J. Guthmiller, A. Bendelac, P. Wilson, B. Roux, E. J. Adams
The paper identifies biochemical determinants of antibody polyreactivity using a bioinformatics pipeline and develops a classifier with over 75% accuracy.
bioRxiv · Jul 30, 2020Immunology