Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of spontaneous SR Ca2+ release
Y. Kurata, K. Tsumoto, K. Hayashi, I. Hisatome, Y. Kuda, M. Tanida
This study investigates the dynamical mechanisms of phase-2 early afterdepolarizations (EADs) in human ventricular myocytes using a modified ten Tusscher-Panfilov model, revealing two distinct EAD initiation mechanisms and their relationship to bifurcation phenomena.
bioRxiv · Apr 18, 2019Physiology