Immune Cells and Inflammatory mediators cause endothelial dysfunction in a vascular microphysiological system
A. Rengarajan, H. E. Goldblatt, D. J. Beebe, M. Virumbrales-Munoz, D. S. Boeldt
This study uses a vascular microphysiological system to show that inflammatory mediators and activated PBMCs disrupt endothelial function by increasing permeability and reducing Ca2+ signaling.
bioRxiv · Sep 27, 2023Bioengineering