Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes
J. Sbierski-Kind, J. Kath, S. Brachs, M. Streitz, M. von Herrath, A. Kuehl, K. Schmidt-Bleek, K. Mai, J. Spranger, H.-D. Volk
This study shows that housing conditions affect adaptive immunity and metabolic outcomes in obesity-induced type 2 diabetes, with antigen-exposed mice showing improved glucose tolerance but liver inflammation.
bioRxiv · Mar 15, 2018Immunology