BiophysicsbioRxiv
Single-molecule assay for proteolytic susceptibility using centrifuge force microscopy:force-induced destabilization of collagen‘s triple helix
M. W. H. Kirkness, N. R. Forde
The paper introduces a method to measure force-dependent proteolytic cleavage using a centrifuge force microscope, showing increased trypsin sensitivity under mechanical load.
DOI 10.1016/j.bpj.2017.12.006