Author

M. Yanagawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Y. Sako· 5 shared M. Abe· 2 shared M. Hiroshima· 2 shared R. Maeda· 2 shared T. Sato· 2 shared H. Tamagaki-Asahina· 1 shared K. Okamoto· 1 shared M. Murata· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersBiophysics

Y. Sako

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Bilateral regulation of EGFR activity and local PI dynamics observed with superresolution microscopy

M. Abe, M. Yanagawa, M. Hiroshima, T. Kobayashi, Y. Sako

This study uses super-resolution microscopy to show that EGFR and PI(4,5)P2 nanodomains coaggregate before EGF stimulation, and their interaction is regulated by phospholipase Cγ and PI(4,5)P2 levels.

bioRxiv · Feb 1, 2024Cell Biology

Threonine phosphorylation regulates the molecular assembly and signaling of EGFR in cooperation with membrane lipids

R. Maeda, H. Tamagaki-Asahina, T. Sato, M. Yanagawa, Y. Sako

This study shows that threonine phosphorylation in EGFR's JM domain switches its function from kinase activation dimers to scaffolding oligomers, influenced by membrane lipids.

bioRxiv · May 14, 2021Biophysics

Total workflows of the single-molecule imaging analysis in living cells: a tutorial guidance to the measurement of the drug effects on a GPCR

M. Yanagawa, Y. Sako

This paper provides a tutorial on using single-molecule imaging to analyze drug effects on GPCRs, including workflows and an open-source software tool.

bioRxiv · Jun 8, 2020 · PreprintBiophysics

Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors

M. Yanagawa, M. Hiroshima, Y. Togashi, M. Abe, T. Yamashita, Y. Shichida, M. Murata, M. Ueda, Y. Sako

The paper uses single-molecule imaging to assess ligand effects on GPCRs by monitoring diffusion dynamics on the cell surface, showing that diffusion coefficients correlate with receptor activity.

bioRxiv · Apr 23, 2018Biophysics

Lipid-protein interplay in dimerization of the juxtamembrane domains of epidermal growth factor receptor

R. Maeda, T. Sato, K. Okamoto, M. Yanagawa, Y. Sako

The paper investigates how lipid-protein interactions and Thr654 phosphorylation regulate EGFR JM dimerization and kinase activity.

bioRxiv · Oct 26, 2017Biophysics