Y. Togashi

Free Energy Landscape of RNA Binding Dynamics in Start Codon Recognition by Eukaryotic Ribosomal Pre-Initiation Complex

This paper uses simulation to evaluate free energy profiles of start codon recognition, showing how mismatches affect translation initiation.

Structural Dynamics of DNA Depending on Methylation Pattern

This study uses molecular dynamics simulations to investigate how DNA methylation patterns affect DNA structure and dynamics, revealing changes in local flexibility and overall geometry.

Histone Tail Dynamics in Partially Disassembled Nucleosomes During Chromatin Remodeling

This study uses molecular dynamics simulations to analyze the dynamics of partially disassembled nucleosomes, finding that DNA deformation is more pronounced in nucleosomes lacking H2A/H2B compared to those lacking H3/H4.

Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors

The paper uses single-molecule imaging to assess ligand effects on GPCRs by monitoring diffusion dynamics on the cell surface, showing that diffusion coefficients correlate with receptor activity.

Bridging the dynamics and organization of chromatin domains by mathematical modeling

This paper uses mathematical modeling to link chromatin domain dynamics and organization by analyzing nucleosome movement in living human cells.