Towards a broad-spectrum antiviral, the myristoyltransferase inhibitor IMP-1088 suppresses viral replication - the Yellow fever NS5 is myristoylated
J. Bodem, M. Immerheiser, M. Zimniak, H. Hilpert, N. Geiger, E.-M. König
The paper shows that IMP-1088, a myristoyltransferase inhibitor, broadly inhibits viral replication across multiple virus families, with Yellow fever NS5 protein myristoylation playing a key role.
bioRxiv · Mar 9, 2021 · PreprintMicrobiology