Author

J. Bodem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E.-M. König· 2 shared H. Obernolte· 2 shared K. Sewald· 2 shared N. Geiger· 2 shared V. Diesendorf· 2 shared A. De Carli· 1 shared A. Mengozzi· 1 shared C. A. Lareau· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

E.-M. König

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

N-acylethanolamine acid amidase inhibition reduces SARS-CoV-2 infection in Human Precision cut-lung slices and downregulates NF-kappaB signalling.

V. La Rocca, C. Filipponi, V. Diesendorf, A. De Carli, G. Sciandrone, S. Nottoli, E. Plicanti, R. Fonnesu, E. Iacono, A. Mengozzi, S. Masi, P. Lenzi, F. Fornai, K. Sewald, H. Obernolte, , M. Lai

This study shows that inhibiting NAAA reduces SARS-CoV-2 replication in human lung tissue and suppresses NF-kappaB signaling.

bioRxiv · Jul 10, 2024 · PreprintMicrobiology

Acetylsalicylic acid and Salicylic acid inhibit SARS-CoV-2 replication in precision-cut lung slices

N. Geiger, E.-M. König, H. Oberwinkler, V. Roll, V. Diesendorf, S. Faehr, H. Obernolte, K. Sewald, S. Wronski, M. Steinke, J. Bodem

The paper investigates whether acetylsalicylic acid and its metabolite salicylic acid inhibit SARS-CoV-2 replication in cell culture and precision-cut lung slices, finding significant suppression of viral replication.

bioRxiv · Aug 9, 2022Microbiology

Towards a broad-spectrum antiviral, the myristoyltransferase inhibitor IMP-1088 suppresses viral replication - the Yellow fever NS5 is myristoylated

J. Bodem, M. Immerheiser, M. Zimniak, H. Hilpert, N. Geiger, E.-M. König

The paper shows that IMP-1088, a myristoyltransferase inhibitor, broadly inhibits viral replication across multiple virus families, with Yellow fever NS5 protein myristoylation playing a key role.

bioRxiv · Mar 9, 2021 · PreprintMicrobiology

A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells

N. Schmidt, C. A. Lareau, H. Keshishian, R. Melanson, M. Zimmer, L. Kirschner, J. Ade, S. Werner, N. Caliskan, E. S. Lander, J. Vogel, S. A. Carr, J. Bodem, M. Munschauer

This study maps direct RNA-protein interactions of SARS-CoV-2 RNA in infected human cells using RAP-MS, identifying host factors, regulators, and potential drug targets involved in viral replication and host defense.

bioRxiv · Jul 15, 2020Microbiology