Author

M.-B. Trujillo-Torralbo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Singanayagam· 2 shared L. J. Finney· 2 shared M. Calderazzo· 2 shared P. Mallia· 2 shared S. L. Johnston· 2 shared A. T. Reid· 1 shared E. Bakhsoliani· 1 shared H. Farne· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

A. Singanayagam

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2 papers

Recent·Most cited

Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon

L. J. Finney, N. Glanville, H. Farne, J. Aniscenko, P. Fenwick, S. Kemp, M.-B. Trujillo-Torralbo, M. Calderazzo, J. A. Wedzicha, P. Mallia, N. W. Bartlett, S. L. Johnston, A. Singanayagam

This study shows inhaled corticosteroids reduce ACE2 expression in COPD, potentially lowering SARS-CoV-2 susceptibility by suppressing type I interferon.

bioRxiv · Jun 13, 2020Immunology

Anti-microbial immunity is impaired in COPD patients with frequent exacerbations

A. Singanayagam, S.-L. Loo, M. Calderazzo, L. J. Finney, M.-B. Trujillo-Torralbo, E. Bakhsoliani, J. L. Girkin, P. C. Veerati, P. S. Pathinayake, K. S. Nichol, A. T. Reid, J. Footitt, S. L. Johnston, N. Bartlett, P. Mallia

This study identifies impaired anti-viral and anti-microbial immunity in COPD patients with frequent exacerbations, linking reduced interferon and MBL-2 levels to increased bacterial loads and susceptibility to exacerbations.

bioRxiv · May 9, 2019 · PreprintImmunology