Polyubiquitin-dependent recruitment of NEMO/IKKγ into T cell receptor signaling microclusters
E. A. DeRiso, A. L. Szymczak-Workman, A. Montecalvo, J. M. Murphy, M.-C. Seminario, L. P. Kane, S. C. Bunnell
This study shows NEMO is recruited into TCR microclusters via polyubiquitin recognition domains, requiring Lck and ZAP-70 but not LAT or SLP-76.
bioRxiv · Apr 30, 2019 · PreprintImmunology