Author

M.-F. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1

Frequent Co-Authors

C.-W. Tsai· 2 shared Y.-C. Tu· 2 shared F.-Y. Chao· 1 shared J. Mount· 1 shared J. Zhang· 1 shared P. Yuan· 1 shared Z. He· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

C.-W. Tsai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure and function of the human mitochondrial MRS2 channel

Z. He, Y.-C. Tu, C.-W. Tsai, J. Mount, J. Zhang, M.-F. Tsai, P. Yuan

This study investigates the structure and function of the human MRS2 channel, revealing its Ca2+-regulated, non-selective ion permeability and a conserved arginine ring that prevents proton motive force collapse.

bioRxiv · Aug 12, 2023Biophysics

Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex

Y.-C. Tu, F.-Y. Chao, M.-F. Tsai

This study identifies dual modulatory effects of spermine on the mitochondrial calcium uniporter complex, showing it enhances activity at low concentrations and inhibits it at high concentrations.

bioRxiv · Jun 6, 2023Biochemistry

MICU1 occludes MCU in the mitochondrial calcium uniporter complex

C.-W. Tsai, M.-F. Tsai

The paper investigates the role of MICU1 in the mitochondrial calcium uniporter complex, showing that MICU1 inhibits Ca2+ currents by blocking the pore, and this inhibition is reversed by a specific mutation.

bioRxiv · Nov 15, 2021Biophysics