PI(4,5)P2 controls slit diaphragm formation and endocytosis in Drosophila nephrocytes
M. Gass, S. Borkowsky, M.-L. Lotz, R. Schroeter, P. Nedvetsky, S. Luschnig, A. Rohlmann, M. Missler, M. P. Krahn
This study shows that PI(4,5)P2 is essential for slit diaphragm formation and endocytosis in Drosophila nephrocytes, while PI(3,4,5)P3 must be tightly regulated for proper nephrocyte development.
bioRxiv · Jun 22, 2021Cell Biology