Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei
C. F. Collett, C. Kitson, N. Baker, H. B. Steele-Stallard, M.-V. Santrot, S. Hutchinson, D. Horn, S. Alsford
This study uses a genome-scale RNAi screen in Trypanosoma brucei to identify drug efficacy determinants for anti-leishmanial drugs, revealing novel targets and resistance mechanisms.
bioRxiv · Apr 13, 2019Microbiology